ANKFY1

ankyrin repeat and FYVE domain containing 1

Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI3P). Involved in homotypic early endosome fusion and to a lesser extend in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the sucellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

ANKFY1 (5)

Publications

No (5)

Tag

Myc-DDK (Flag) (5)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (3)

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Human ANKFY1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90367

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.3 kDa

Price:

20 µg/$215

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Human ANKFY1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90368

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

20 µg/$215

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Human ANKFY1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71681

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

20 µg/$1,107

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ANKFY1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G112653

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

128.3 kDa

Price:

100 µg/$710

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ANKFY1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111049

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.6 kDa

Price:

100 µg/$710

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