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ANTXR2 / CMG2 is a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | anthrax toxin receptor 2 |
Synonyms: | ANTXR2, Anthrax toxin receptor 2, CMG2, CMG-2, JHF, ISH |
Target Sequences: | NM_058172 NP_477520.2 P58335 |
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