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ANXA9

annexin A9

The annexins are a family of calcium-dependent phospholipid-binding proteins. Annexin 31 cDNA encodes a 338-amino acid protein with less than 40% identity to other annexins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin 31 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin 31 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.

Gene Name: annexin A9
Synonyms: ANXA9, Annexin A9, Annexin XXXI, Annexin-9, ANX31, Pemphaxin, Annexin 31, Annexin-31
Target Sequences: NM_003568 NP_003559.2 O76027

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
ANXA9 (7)
No (7)
GST (1)
GST, N-terminus (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ANXA9 Protein - 12.5% SDS-PAGE of human ANXA9 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.92 kDa
10 µg/$479; 25 µg/$670
ANXA9 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
38.2 kDa
20 µg/$150
ANXA9 Protein - Purified recombinant protein ANXA9 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
38.2 kDa
20 µg/$1,107
ANXA9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
38.2 kDa
100 µg/$494
ANXA9 Protein
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E. coli
His-SUMO
53.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
ANXA9 Protein - Recombinant  Annexin A9 By SDS-PAGE
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E. coli
His-GST
68.4 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).