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This locus encodes both the light and heavy subunits of acyloxyacyl hydrolase. The encoded enzyme catalyzes the hydrolysis of acyloxylacyl-linked fatty acyl chains from bacterial lipopolysaccharides, effectively detoxifying these molecules. The encoded protein may play a role in modulating host inflammatory response to gram-negative bacteria. Alternatively spliced transcript variants have been described.
Gene Name: | acyloxyacyl hydrolase (neutrophil) |
Synonyms: | AOAH, Acyloxyacyl hydrolase |
Target Sequences: | NM_001637 NP_001628.1 P28039 |
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