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AP1AR

adaptor-related protein complex 1 associated regulatory protein

Necessary for adaptor protein complex 1 (AP-1)-dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/gamma1-adaptin, one of the subunits of the AP-1 adaptor complex. The direct interaction with AP1G1/gamma1-adaptin attenuates the release of the AP-1 complex from membranes. Regulates endosomal membrane traffic via association with AP-1 and KIF5B thus linking kinesin-based plus-end-directed microtubular transport to AP-1-dependent membrane traffic. May act as effector of AP-1 in calcium-induced endo-lysosome secretion. Inhibits Arp2/3 complex function; negatively regulates cell spreading, size and motility via intracellular sequestration of the Arp2/3 complex.

Gene Name: adaptor-related protein complex 1 associated regulatory protein
Synonyms: AP1AR, 2C18, Gamma-BAR, GBAR, PRO0971, C4orf16
Target Sequences: NM_018569 NP_061039.3 Q63HQ0

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Proteins (5)
Over-Expression Lysate (4)
Recombinant (1)
AP1AR (5)
No (5)
His (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Purified (1)
AP1AR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
30.3 kDa
20 µg/$150
AP1AR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.1 kDa
20 µg/$150
AP1AR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
30.3 kDa
100 µg/$494
AP1AR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.1 kDa
100 µg/$494
AP1AR Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).