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AP5Z1

adaptor-related protein complex 5, zeta 1 subunit

AP5Z1 was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862).

Gene Name: adaptor-related protein complex 5, zeta 1 subunit
Synonyms: AP5Z1, AP-5 complex subunit zeta-1, SPG48, Zeta, Zeta5, KIAA0415
Target Sequences: NM_014855 NP_055670.1 O43299

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Products
Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
AP5Z1 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
AP5Z1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
88.4 kDa
100 µg/$710
AP5Z1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
88.4 kDa
20 µg/$215
AP5Z1 Protein - 12.5% SDS-PAGE of human AP5Z1 stained with Coomassie Blue
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Wheat Germ Extract
GST
74.8 kDa
10 µg/$479; 25 µg/$670
Viewing 1-3 of 3 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).