APC

Adenomatous Polyposis Coli

Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.

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Products

Antibodies (67)

Type

Primary (67)

Target

APC (67)

Reactivity

Human (45)

Mouse (29)

Rat (21)

Bovine (1)

Chicken (1)

Monkey (2)

Pig (3)

Application

IHC (28)

IHC-Fr (1)

IHC-P (9)

WB (55)

ELISA (16)

ICC (1)

IF (8)

IP (3)

Peptide-ELISA (5)

Host

rabbit (59)

mouse (6)

goat (1)

rat (1)

Product Group

PathPlus Cancer (1)

Isotype

IgG (31)

IgG1 (5)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (7)

polyclonal pc (60)

Clone

3E2 (1)

OTI1B12 (2)

OTI2B8 (2)

Format

APC (2)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (5)

Carrier-free (2)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (4)

PE Conjugated (4)

Unconjugated (41)

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Epitope

aa2634-2842 (8)

aa2636-2845 (8)

aa1148-1176 (7)

pSer2054 (6)

aa955-1382 (4)

aa2634-2843 (3)

aa1-50 (2)

1990-2070 aa (1)

2770-2850 aa, C-terminal (1)

Ab-2054 (1)

C-Terminus (1)

Gln2829 (1)

Internal (1)

Lys2050 (1)

aa1-433 (1)

aa2020-2069 (1)

aa2537-2843 (1)

aa2793-C-term (1)

aa2794-2843 (1)

aa75-125 (1)

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Publications

No (67)

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APC Antibody (2770-2850 aa, C-terminal) LS-C382049

Antibody:

APC Rabbit anti-Human Polyclonal (2770-2850 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PathPlus™ APC Antibody (aa2794-2843) LS-B7592

Cancer

(5.0) Rating

Antibody:

APC Rabbit anti-Human Polyclonal (aa2794-2843) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$440

Select

APC Antibody (aa1-50) LS-C286501

Antibody:

APC Rabbit anti-Human Polyclonal (aa1-50) Antibody

Reactivity:

Human

Applications:

IHC

Format:

Unconjugated

Price:

2.5 µg/$295; 100 µl/$532

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APC Antibody (C-Terminus) LS-C351831

Antibody:

APC Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Chicken, Bovine, Rat, Pig, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

APC Antibody (phospho-Ser2054) LS-C351830

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$315

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APC Antibody (clone 3E2) LS-C196665

Antibody:

APC Mouse anti-Human Monoclonal (3E2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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APC Antibody (Internal) LS-C358903

Antibody:

APC Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

APC Antibody (aa1148-1176) LS-C319524

Antibody:

APC Rabbit anti-Human Polyclonal (aa1148-1176) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

APC Antibody (phospho-Ser2054) LS-C800672

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

APC Antibody LS-C808424

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

APC Antibody (Gln2829) LS-C175922

Antibody:

APC Rabbit anti-Human Polyclonal (Gln2829) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

APC Antibody (aa955-1382, clone OTI2B8) LS-C338825

Antibody:

APC Mouse anti-Human Monoclonal (aa955-1382) (OTI2B8) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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APC Antibody (aa955-1382, clone OTI2B8, Carrier-free) LS-C798087

Antibody:

APC Mouse anti-Human Monoclonal (aa955-1382) (Carrier-free) (OTI2B8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

APC Antibody LS-C834137

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

APC Antibody (phospho-Ser2054) LS-C198632

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

APC Antibody (1990-2070 aa) LS-C381316

Antibody:

APC Rabbit anti-Human Polyclonal (1990-2070 aa) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

APC Antibody (aa1-433) LS-C3765

Antibody:

APC Mouse anti-Human Monoclonal (aa1-433) Antibody

Reactivity:

Human

Applications:

IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

50 µg/$558

Select

APC Antibody (phospho-Ser2054) LS-C822179

Antibody:

APC Rabbit anti-Human Polyclonal (pSer2054) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

APC Antibody (aa2537-2843) LS-C34992

Antibody:

APC Goat anti-Human Polyclonal (aa2537-2843) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$940

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APC Antibody LS-C126824

Antibody:

APC Rat anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µg/$564

Select

APC Antibody LS-C825889

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

APC Antibody LS-C659448

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$331

Select

APC Antibody (aa2020-2069) LS-C117827

Antibody:

APC Rabbit anti-Human Polyclonal (aa2020-2069) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

APC Antibody (Ab-2054) LS-C822178

Antibody:

APC Rabbit anti-Human Polyclonal (Ab-2054) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

APC Antibody LS-C416163

Antibody:

APC Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

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