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May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.
Gene Name: | amyloid beta (A4) precursor-like protein 1 |
Synonyms: | APLP1, APLP-1, APLP, Amyloid-like protein 1 |
Target Sequences: | NM_005166 NP_005157.1 P51693 |
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