Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
APOBEC3A is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
Synonyms: | APOBEC3A, ARP3, BK150C2.1, Phorbolin i, Phorbolin-1, PHRBN, Phorbolin 1 |
Target Sequences: | NM_145699 AAA03706.2 P31941 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.