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APOBEC3B

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. Exhibits antiviral activity against simian immunodeficiency virus (SIV), hepatitis B virus (HBV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons.

Gene Name: Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
Synonyms: APOBEC3B, APOBEC1L, ARCD3, BK150C2.2, Cytidine deaminase, DJ742C19.2, Phorbolin 2, Phorbolin-1-related protein, PHRBNL, ARP4, Phorbolin 3, Phorbolin-2/3
Target Sequences: NM_004900 NP_004891.4 Q9UH17

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Products
Antibodies (18)
Primary (18)
APOBEC3B (18)
Human (16)
Mouse (7)
Rat (1)
IHC (1)
IHC-P (2)
WB (17)
ELISA (8)
IF (1)
IP (2)
rabbit (17)
mouse (1)
Product Group
PathPlus Cancer (2)
IgG (16)
polyclonal pc (18)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Preservative Free (1)
Unconjugated (10)
aa299-330 (6)
aa78-127 (4)
No (18)
APOBEC3B Antibody - Human Breast Carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
APOBEC3B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC-P, WB
Unconjugated
0.05 mg/$460
APOBEC3B Antibody - Western blot analysis of extracts of various cell lines.
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APOBEC3B Rabbit anti-Human Polyclonal Antibody
WB
Unconjugated
20 µl/$275; 100 µl/$389
APOBEC3B Antibody
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APOBEC3B Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
50 µl/$286; 100 µl/$321
APOBEC3B Antibody - Human Breast Carcinoma: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
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APOBEC3B Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
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APOBEC3B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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APOBEC3B Rabbit anti-Human Polyclonal (aa299-330) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
APOBEC3B Antibody - Anti-APOBEC3B rabbit polyclonal antibody at 1:500 dilution. Lane A: HepG2 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 46 kDa. Observed band size: 50 kDa. (We are unsure as to the identity of these extra bands.)
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APOBEC3B Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IP, WB
Unconjugated, Preservative Free
100 µl/$412
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APOBEC3B Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
APOBEC3B Antibody - HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOBEC3B Rabbit anti-Human Polyclonal (aa78-127) Antibody
Human
WB
Unconjugated
100 µl/$424
APOBEC3B Antibody - HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOBEC3B Rabbit anti-Human Polyclonal (aa78-127) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
APOBEC3B Antibody - HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOBEC3B Rabbit anti-Human Polyclonal (aa78-127) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
APOBEC3B Antibody - HepG2 cell lysate. Antibody concentration: 0.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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APOBEC3B Rabbit anti-Human Polyclonal (aa78-127) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
Select
APOBEC3B Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-18 of 18 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).