APOBEC3F / ARP8

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA. Exhibits antiviral activity also against hepatitis B virus (HBV), equine infectious anemia virus (EIAV), xenotropic MuLV-related virus (XMRV) and simian foamy virus (SFV) and may inhibit the mobility of LTR and non-LTR retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.

☰ Filters

Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

APOBEC3F / ARP8 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

Human APOBEC3F / ARP8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88101

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.8 kDa

Price:

20 µg/$150

Select

APOBEC3F / ARP8 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106667

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.8 kDa

Price:

100 µg/$494

Select

Human APOBEC3F / ARP8 Protein (Recombinant GST) (Full Length) - LS-G36950

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

38.2 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human APOBEC3F / ARP8 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70827

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.8 kDa

Price:

20 µg/$1,107

Select

Human APOBEC3F / ARP8 Protein (Recombinant GST, N-terminus) (aa274-372) - LS-G63805

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-5 of 5 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.