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APOC3 / Apolipoprotein C III

apolipoprotein C-III

Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors.

Gene Name: apolipoprotein C-III
Synonyms: APOC3, Apo-CIII, Apolipoprotein C3, APOCIII, HALP2, ApoC-III, Apolipoprotein C-III
Target Sequences: NM_000040 NP_000031.1 P02656

Publications (2)

1
Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum. Wang Y, Song Z, Wagner JD, Pachuk C, Subramanian RR. Journal of lipid research. 2011 52:1265-71. [PubMed:21371998] [PMC:PMC3090247]
2
Lowering apolipoprotein CIII protects against high-fat diet-induced metabolic derangements. Ismael Valladolid-Acebes, Karin Åvall, Patricia Recio-López, Noah Moruzzi, Galyna Bryzgalova, Marie Björnholm, Anna Krook, Elena Fauste Alonso, Madelene Ericsson, Fredrik Landfors, Stefan K Nilsson, Per-Olof Berggren, Lisa Juntti-Berggren. Science advances. 2021 March;7:eabc2931. [Full Text Article] [PubMed:33712458] [PMC:PMC7954448]

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
APOC3 / Apolipoprotein C III (13)
No (13)
6His-SUMO, N-terminus (2)
GST, N-terminus (2)
His (2)
His, N-Terminal (1)
His-GST (1)
His-SUMO (1)
MBP, N-terminus + 6His, C-terminus (1)
Myc-DDK (Flag) (3)
Crab-eating macaque (2)
Human (6)
Mouse (2)
Rat (2)
293T Cells (1)
Baculovirus (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Yeast (2)
Purified (3)
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His, N-Terminal
21 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
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E. coli
6His-SUMO, N-terminus
12.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
APOC3 / Apolipoprotein C III Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His-SUMO, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His-GST
40.7 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
APOC3 / Apolipoprotein C III Protein - Recombinant Apolipoprotein C3 By SDS-PAGE
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E. coli
His
10.5 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
APOC3 / Apolipoprotein C III Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Wheat Germ Extract
GST, N-terminus
25 µg/$670; 10 µg/$479
APOC3 / Apolipoprotein C III Protein - Purified recombinant protein APOC3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
8.7 kDa
20 µg/$1,107
APOC3 / Apolipoprotein C III Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Baculovirus
MBP, N-terminus + 6His, C-terminus
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
APOC3 / Apolipoprotein C III Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
10.85 kDa
100 µg/$494
APOC3 / Apolipoprotein C III Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
10.85 kDa
20 µg/$150
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E. coli
His-SUMO
24.8 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
APOC3 / Apolipoprotein C III Protein
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Yeast
His
11 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).