APP / Beta Amyloid Precursor

amyloid beta (A4) precursor protein

Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu2+-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalization of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu2+ ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1.

☰ Filters

Products

ELISA Kits (26)

Type

Cell-Based Phosphorylation (1)

Custom (2)

Sandwich (21)

Sandwich CLIA (2)

Target

APP / Beta Amyloid Precursor (26)

Reactivity

Human (12)

Mouse (3)

Rat (6)

Bovine (1)

Chicken (1)

Dog (1)

Monkey (1)

Pig (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (4)

96-Well Strip Plate (21)

Publications

No (26)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (5)

Cell Lysates (1)

Cell Supernatant (1)

Plasma (20)

Serum (20)

Tissue Homogenates (6)

Select

Mouse APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F8583

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

Select

Mouse APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F15450

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$585

Select

Rat APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F20815

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Rat APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F10698

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Rat APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F6931

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$750

Select

Rabbit APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F41041

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

15.63 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F4395

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F23989

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

78.13 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F26637

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Rat APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F27330

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

2.5 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F3319

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.137 - 33.33 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$760

Select

Mouse/Human/Rat Phospho-APP / Beta Amyloid Precursor (Thr743/668) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1034

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F13041

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Bovine APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F13042

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Bovine

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

Select

Dog APP / Beta Amyloid Precursor (Custom ELISA) ELISA Kit - LS-F15451

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Dog

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Pig APP / Beta Amyloid Precursor (Custom ELISA) ELISA Kit - LS-F15452

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Chicken APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F41038

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

15.625 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F41039

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F41040

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human APP / Beta Amyloid Precursor (CLIA) ELISA Kit - LS-F29796

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F39639

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$766

Select

Rat APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F39640

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$717

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F74701

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Supernatant, Plasma, Serum

Price:

1 Plate/$598

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F24363

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

312 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$624

Select

Human APP / Beta Amyloid Precursor (Sandwich ELISA) ELISA Kit - LS-F24364

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$624

Viewing 1-25 of 26 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: ELISA Kits

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.