Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
AQP2 / Aquaporin 2
aquaporin 2 (collecting duct)
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2. Hoffert JD, Fenton RA, Moeller HB, Simons B, Tchapyjnikov D, McDill BW, Yu MJ, Pisitkun T, Chen F, Knepper MA. The Journal of biological chemistry. 2008 283:24617-27.
[PubMed:18606813]
[PMC:PMC2528999]
2
Serine 269 phosphorylated aquaporin-2 is targeted to the apical membrane of collecting duct principal cells. Moeller HB, Knepper MA, Fenton RA. Kidney international. 2009 75:295-303.
[PubMed:18843259]
[PMC:PMC3502047]
3
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct. Yu MJ, Miller RL, Uawithya P, Rinschen MM, Khositseth S, Braucht DW, Chou CL, Pisitkun T, Nelson RD, Knepper MA. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:2441-6.
[PubMed:19190182]
[PMC:PMC2650175]
4
Localization of aquaporins 1, 2, and 3 and vasopressin type 2 receptor in the mouse inner ear. Takumida M, Kakigi A, Egami N, Nishioka R, Anniko M. Acta oto-laryngologica. 2012 132:807-13. (ICC, IHC; Mouse)
[PubMed:22768909]
5
Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus. Trimpert C, van den Berg DT, Fenton RA, Klussmann E, Deen PM. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2012 27:4389-97. (WB, DB; Dog)
[PubMed:22778181]
6
Deficiency of the calcium-sensing receptor in the kidney causes parathyroid hormone-independent hypocalciuria. Toka HR, Al-Romaih K, Koshy JM, DiBartolo S, Kos CH, Quinn SJ, Curhan GC, Mount DB, Brown EM, Pollak MR. Journal of the American Society of Nephrology : JASN. 2012 23:1879-90.
[PubMed:22997254]
[PMC:PMC3482734]
7
Induction of metabolic acidosis with ammonium chloride (NH4Cl) in mice and rats--species differences and technical considerations. Nowik M, Kampik NB, Mihailova M, Eladari D, Wagner CA. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2011 26:1059-72. (WB; Rat)[Full Text Article]
[PubMed:21220937]
8
Aquaporin-2 plays an important role in water transportation through the bladder wall in rats. Yosuke Morizawa, Kazumasa Torimoto, Shunta Hori, Daisuke Gotoh, Yasushi Nakai, Makito Miyake, Akihide Hirayama, Nobumichi Tanaka, Kiyohide Fujimoto. Neurourology and urodynamics. 2018 November;37:2434-2440. [Full Text Article]
[PubMed:29797427]
Related Antibodies: LS-C312893.
9
Sodium plays an important role in the absorption of intravesical fluid. Yosuke Morizawa, Kazumasa Torimoto, Shunta Hori, Daisuke Gotoh, Yasushi Nakai, Makito Miyake, Nobumichi Tanaka, Akihide Hirayama, Kiyohide Fujimoto. Lower urinary tract symptoms. 2021 Janurary;13:177-182. [Full Text Article]
[PubMed:32410367]
Related Antibodies: LS-C312893.
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).