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AQP2 / Aquaporin 2
aquaporin 2 (collecting duct)
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
| Gene Name: | aquaporin 2 (collecting duct) |
| Family/Subfamily: | Transporter , Aquaporin |
| Synonyms: | AQP2, AQP-CD, ADH water channel, Aquaporin 2 (collecting duct), AQP-2, Aquaporin 2, Aquaporin-CD, Aquaporin-2, Water-channel aquaporin 2, WCH-CD |
| Target Sequences: | NM_000486 NP_000477.1 P41181 |
Publications (9)
1
Vasopressin-stimulated increase in phosphorylation at Ser269 potentiates plasma membrane retention of aquaporin-2. Hoffert JD, Fenton RA, Moeller HB, Simons B, Tchapyjnikov D, McDill BW, Yu MJ, Pisitkun T, Chen F, Knepper MA. The Journal of biological chemistry. 2008 283:24617-27.
[PubMed:18606813]
[PMC:PMC2528999]
2
Serine 269 phosphorylated aquaporin-2 is targeted to the apical membrane of collecting duct principal cells. Moeller HB, Knepper MA, Fenton RA. Kidney international. 2009 75:295-303.
[PubMed:18843259]
[PMC:PMC3502047]
3
Systems-level analysis of cell-specific AQP2 gene expression in renal collecting duct. Yu MJ, Miller RL, Uawithya P, Rinschen MM, Khositseth S, Braucht DW, Chou CL, Pisitkun T, Nelson RD, Knepper MA. Proceedings of the National Academy of Sciences of the United States of America. 2009 106:2441-6.
[PubMed:19190182]
[PMC:PMC2650175]
☰ Filters
Products
Proteins
(5)
Type
Over-Expression Lysate
(2)
Recombinant
(3)
Target
AQP2 / Aquaporin 2
(5)
Publications
No
(5)
Tag
GST
(1)
His
(1)
His-GST
(1)
Myc-DDK (Flag)
(2)
Species
Human
(4)
Source
293T Cells
(1)
E. coli
(2)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Low Endotoxin Level
Low endotoxin level
(1)
Wheat Germ Extract
GST
55.2 kDa
10 µg/$479; 25 µg/$670
E. coli
His-GST
42.6 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
293T Cells
Myc-DDK (Flag)
28.7 kDa
20 µg/$150
E. coli
71 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
7.92 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
HEK 293 Cells
Myc-DDK (Flag)
28.7 kDa
100 µg/$494
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