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AQP4 / Aquaporin 4
aquaporin 4
AQP4, also known as Mercurial-insensitive water channel (MIWC), is the fourth member of the aquaporin water channel family. This osmoreceptor regulates body water balance and mediates water flow within the central nervous system. It appears to play some specific role in the functioning of skeletal muscles, retina, and auditory system. Contrary to other aquaporin family members, AQP4 is not inhibited by mercurial compounds. The expression of AQP4 is reduced in the skeletal muscles of Duchenne muscular dystrophy syndrome patients. In addition, a dysfunction of the AQP4 may contribute to the development of brain edema; some results indicate that interference with the subcellular localization of this protein may have a therapeutic potential for delaying the onset of this pathological condition.
| Gene Name: | aquaporin 4 |
| Family/Subfamily: | Transporter , Aquaporin |
| Synonyms: | AQP4, Aquaporin type4, Aquaporin 4, Aquaporin-4, HMIWC2, MIWC, WCH4, AQP-4 |
| Target Sequences: | NM_001650 NP_001641.1 P55087 |
Publications (5)
1
Aquaporin pathways and mucin secretion of Bowman's glands might protect the olfactory mucosa. Solbu TT, Holen T. Chemical senses. 2012 37:35-46. (IHC; Rat)
[Full Text Article]
[PubMed:21745799]
Related Antibodies: LS-C3805.
2
Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury. Li W, Tan C, Liu Y, Liu X, Wang X, Gui Y, Qin L, Deng F, Yu Z, Hu C, Chen L. Molecular medicine reports. 2015 November;12:7756-62. (Human)
[Full Text Article]
[PubMed:26458999]
Related Antibodies: LS-C3805.
3
Palmitoylethanolamide and Cannabidiol Prevent Inflammation-induced Hyperpermeability of the Human Gut In Vitro and In Vivo-A Randomized, Placebo-controlled, Double-blind Controlled Trial. Daniel G Couch, Hollie Cook, Catherine Ortori, Dave Barrett, Jonathan N Lund, Saoirse E O'Sullivan. Inflammatory bowel diseases. 2019 May;25:1006-1018. [Full Text Article]
[PubMed:31054246]
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AQP4 / Aquaporin 4 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rat, Gibbon, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (aa258-274) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (200-300 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
E. coli
His-GST
47.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$587
E. coli
His-SUMO
23.98 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
AQP4 / Aquaporin 4 Rabbit anti-Rat Polyclonal (aa280-296) Antibody
Rat
ELISA, IHC, WB
Unconjugated
100 µg/$832
AQP4 / Aquaporin 4 Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µg/$442
AQP4 / Aquaporin 4 Rabbit anti-Rat Polyclonal (aa273-291) (FITC) Antibody
Mouse, Rat, Human
IF, WB
FITC Conjugated
100 µg/$472
AQP4 / Aquaporin 4 Rabbit anti-Rat Polyclonal (aa273-291) (RPE) Antibody
Mouse, Rat, Human
IF, WB
RPE Conjugated
100 µg/$477
E. coli
His
15.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
AQP4 / Aquaporin 4 Mouse anti-Human Monoclonal (aa301-318) (Concentrated) (3D2) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Concentrated
100 µg/$938
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$575
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (aa230-260) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
AQP4 / Aquaporin 4 Rabbit anti-Rat Polyclonal (aa280-296) Antibody
Rat
ELISA, IHC, WB
Unconjugated
100 µl/$801
AQP4 / Aquaporin 4 Rabbit anti-Mouse Polyclonal (aa177-304) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535
AQP4 / Aquaporin 4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$564
AQP4 / Aquaporin 4 Rabbit anti-Mouse Polyclonal (Preservative Free) (Biotin) Antibody
Mouse
ELISA
Biotin Conjugated, Preservative Free
50 µg/$343
AQP4 / Aquaporin 4 Mouse anti-Human Monoclonal (PE) Antibody
Rat, Human
WB
PE Conjugated
100 µl/$399; 200 µl/$479; 500 µl/$822; 1 ml/$978; 2 ml/$1,255; 5 ml/$2,353
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