ARF1

ADP-ribosylation factor 1

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).

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Products

Proteins (16)

Type

Over-Expression Lysate (9)

Recombinant (7)

Target

ARF1 (16)

Publications

No (16)

Tag

10His-GST, N-terminus + Myc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (12)

Species

Human (12)

Source

293T Cells (5)

E. coli (2)

HEK 293 Cells (7)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human ARF1 Protein (Recombinant His) - LS-G867

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human ARF1 Protein (Recombinant GST, N-terminus) (aa82-181) - LS-G57801

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ARF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64849

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$1,107

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Human ARF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64850

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$1,107

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Human ARF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64851

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$1,107

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Human ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74345

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$150

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Human ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74346

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$150

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Human ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74347

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$150

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Human ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74349

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$150

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Human ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74350

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

20 µg/$150

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ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121163

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

100 µg/$494

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ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121165

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

100 µg/$494

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ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121166

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

100 µg/$494

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ARF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118472

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

20.5 kDa

Price:

100 µg/$494

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Human ARF1 Protein (Recombinant GST) (Full Length) - LS-G27505

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

45.65 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARF1 Protein (Recombinant 10His-GST, N-terminus + Myc, C-terminus) (aa2-181) - LS-G56099

Source:

E. coli

Tag:

10His-GST, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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