ARHGAP24

Rho GTPase Activating Protein 24

Rho GTPase-activating protein involved in cell polarity, cell morphology and cytoskeletal organization. Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state. Controls actin remodeling by inactivating Rac downstream of Rho leading to suppress leading edge protrusion and promotes cell retraction to achieve cellular polarity. Able to suppress RAC1 and CDC42 activity in vitro. Overexpression induces cell rounding with partial or complete disruption of actin stress fibers and formation of membrane ruffles, lamellipodia, and filopodia. Isoform 2 is a vascular cell-specific GAP involved in modulation of angiogenesis.

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Proteins (9)

Type

Over-Expression Lysate (6)

Recombinant (3)

Target

ARHGAP24 (9)

Publications

No (9)

Tag

GST (1)

His, N-Terminal (1)

Myc-DDK (Flag) (7)

Species

Human (6)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ARHGAP24 Protein (Recombinant GST) (Full Length) - LS-G35566

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

99.7 kDa

Price:

2 µg/$439

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Human ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84306

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.1 kDa

Price:

20 µg/$215

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Human ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84307

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.1 kDa

Price:

20 µg/$215

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Human ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84308

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.2 kDa

Price:

20 µg/$215

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Human ARHGAP24 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69304

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.1 kDa

Price:

20 µg/$1,107

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ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109248

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.2 kDa

Price:

100 µg/$710

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ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119621

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

73.1 kDa

Price:

100 µg/$710

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ARHGAP24 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121001

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

84.1 kDa

Price:

100 µg/$710

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Human ARHGAP24 Protein (Recombinant His, N-Terminal) - LS-G144659

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

73.1 kDa

Price:

50 µg/$419

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