ARHGDIA / RHOGDI

Rho GDP dissociation inhibitor (GDI) alpha

Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.

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Products

Proteins (11)

Type

Over-Expression Lysate (4)

Recombinant (7)

Target

ARHGDIA / RHOGDI (11)

Publications

No (11)

Tag

GST (3)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (9)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (4)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human ARHGDIA / RHOGDI Protein (Recombinant GST) (Full Length) - LS-G22043

Source:

E. coli

Tag:

GST

Molecular Weight:

50.5 kD

Price:

100 µg/$420; 20 µg/$323; 1 mg/$1,355

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Human ARHGDIA / RHOGDI Protein (Recombinant GST, N-terminus) (aa59-137) - LS-G57811

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ARHGDIA / RHOGDI Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66875

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23 kDa

Price:

20 µg/$1,107

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Human ARHGDIA / RHOGDI Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66877

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.7 kDa

Price:

20 µg/$1,107

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ARHGDIA / RHOGDI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100254

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23 kDa

Price:

100 µg/$494

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ARHGDIA / RHOGDI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130731

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.7 kDa

Price:

100 µg/$494

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Human ARHGDIA / RHOGDI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78642

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

23 kDa

Price:

20 µg/$150

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Human ARHGDIA / RHOGDI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78643

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.7 kDa

Price:

20 µg/$150

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Human ARHGDIA / RHOGDI Protein (Recombinant GST) (Full Length) - LS-G27519

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.18 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARHGDIA / RHOGDI Protein (Recombinant GST) (Full Length) - LS-G27520

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.18 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARHGDIA / RHOGDI Protein (Recombinant His) - LS-G1000

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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