ARHGEF3 / XPLN

Rho guanine nucleotide exchange factor (GEF) 3

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (8)

Type

Over-Expression Lysate (6)

Recombinant (2)

Target

ARHGEF3 / XPLN (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (5)

Source

293T Cells (3)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human ARHGEF3 / XPLN Protein (Recombinant GST) (Full Length) - LS-G33547

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human ARHGEF3 / XPLN Protein (Recombinant GST, N-terminus) (aa33-142) - LS-G62376

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91142

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.6 kDa

Price:

20 µg/$150

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Human ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91144

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.6 kDa

Price:

20 µg/$150

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Human ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91143

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.6 kDa

Price:

20 µg/$150

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ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111379

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.6 kDa

Price:

100 µg/$494

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ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124825

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.6 kDa

Price:

100 µg/$494

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ARHGEF3 / XPLN Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124826

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

60.6 kDa

Price:

100 µg/$494

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