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ARL4C
ADP-ribosylation factor-like 4C
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.
| Gene Name: | ADP-ribosylation factor-like 4C |
| Synonyms: | ARL4C, ADP-ribosylation factor-like 7, ARL7, LAK |
| Target Sequences: | NM_005737 NP_005728.2 P56559 |
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