ARTS1 / ERAP1

endoplasmic reticulum aminopeptidase 1

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

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Products

Proteins (10)

Type

Over-Expression Lysate (6)

Recombinant (4)

Target

ARTS1 / ERAP1 (10)

Publications

No (10)

Tag

10His, N-terminus + Myc, C-terminus (1)

GST, N-terminus (1)

Myc-DDK (Flag) (8)

Species

Human (6)

Mouse (1)

Source

293T Cells (3)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ARTS1 / ERAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67469

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.7 kDa

Price:

20 µg/$1,107

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Human ARTS1 / ERAP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67470

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.1 kDa

Price:

20 µg/$1,107

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Human ARTS1 / ERAP1 Protein (Recombinant GST, N-terminus) (aa832-941) - LS-G62533

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse ARTS1 / ERAP1 Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (aa731-930) - LS-G56238

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79918

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.1 kDa

Price:

20 µg/$150

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Human ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79919

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.1 kDa

Price:

20 µg/$215

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Human ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79920

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.7 kDa

Price:

20 µg/$215

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ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123807

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.1 kDa

Price:

100 µg/$710

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ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120340

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.1 kDa

Price:

100 µg/$494

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ARTS1 / ERAP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101433

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.7 kDa

Price:

100 µg/$710

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