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ASB2

ankyrin repeat and SOCS box containing 2

ASB2 is a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: ankyrin repeat and SOCS box containing 2
Synonyms: ASB2, ASB-2
Target Sequences: NM_016150 NP_057234.2 Q96Q27

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
ASB2 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
ASB2 Protein - 12.5% SDS-PAGE of human ASB2 stained with Coomassie Blue
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Wheat Germ Extract
GST
90.31 kDa
2 µg/$439
ASB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
64.9 kDa
20 µg/$150
ASB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
64.9 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).