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ASB6 belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene.
Gene Name: | ankyrin repeat and SOCS box containing 6 |
Synonyms: | ASB6, ASB-6 |
Target Sequences: | NM_017873 NP_060343.1 Q9NWX5 |
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