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ASCL2 is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Gene Name: | achaete-scute family bHLH transcription factor 2 |
Synonyms: | ASCL2, Achaete-scute homolog 2, Achaete-scute complex-like 2, ASH-2, ASH2, BHLHa45, HASH2, MASH2 |
Target Sequences: | NM_005170 NP_005161.1 Q99929 |
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