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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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ASTL
Astacin-like metallo-endopeptidase (M12 family)
Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.
| Gene Name: | Astacin-like metallo-endopeptidase (M12 family) |
| Synonyms: | ASTL |
| Target Sequences: | NP_001002036.3 |
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