ASXL2

additional sex combs like 2 (Drosophila)

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity). Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

ASXL2 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human ASXL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86605

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

153.6 kDa

Price:

20 µg/$215

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ASXL2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111851

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

153.6 kDa

Price:

100 µg/$710

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