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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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ATF7

activating transcription factor 7

Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.Isoform 4/ATF-A0 acts as a dominant repressor of the E-selectin/NF-ELAM1/delta-A promoter.Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation.

Gene Name: activating transcription factor 7
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: ATF7, ATFA, Transcription factor ATF-A
Target Sequences: NM_006856 NP_006847.1 P17544

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Products
ELISA Kits (8)
Cell-Based (1)
DNA Binding (1)
Sandwich (6)
ATF7 (8)
Human (3)
Mouse (2)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (6)
No (8)
Adherent Cell Cultures (1)
Cell Lysates (1)
Nuclear Lysates (1)
Plasma (1)
Serum (1)
ATF7 ELISA Kit
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DNA Binding
12 x 8-Well Microstrips
Mouse, Human
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
ATF7 ELISA Kit
Select
Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
ATF7 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
ATF7 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATF7 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATF7 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATF7 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
ATF7 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).