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Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.
Gene Name: | autophagy related 14 |
Synonyms: | ATG14, Autophagy related 14, Beclin 1-Interacting protein, KIAA0831, ATG14L, BARKOR |
Target Sequences: | AB020638 BAA74854.2 Q6ZNE5 |
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