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ATG16L1 / ATG16L

autophagy related 16-like 1 (S. cerevisiae)

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Gene Name: autophagy related 16-like 1 (S. cerevisiae)
Synonyms: ATG16L1, APG16-like 1, APG16L, APG16L beta, ATG16L, Autophagy-related protein 16-1, IBD10, WD repeat domain 30, ATG16A, WDR30
Target Sequences: NM_017974 NP_060444.3 Q676U5

Publications (7)

1
Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong DJ, Philpott DJ, van der Meer JW, Girardin SE, Joosten LA, Netea MG. Gut. 2011 60:1229-35. [PubMed:21406388]
2
Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease. Nascimento-Ferreira I, Santos-Ferreira T, Sousa-Ferreira L, Auregan G, Onofre I, Alves S, Dufour N, Colomer Gould VF, Koeppen A, Dglon N, Pereira de Almeida L. Brain : a journal of neurology. 2011 134:1400-15. [PubMed:21478185] Related Antibodies: LS-C156571.
3
NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans. Jurez E, Carranza C, Hernndez-Snchez F, Len-Contreras JC, Hernndez-Pando R, Escobedo D, Torres M, Sada E. European journal of immunology. 2012 42:880-9. (Human) [PubMed:22531915]
4
Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Tattoli I, Sorbara MT, Vuckovic D, Ling A, Soares F, Carneiro LA, Yang C, Emili A, Philpott DJ, Girardin SE. Cell host & microbe. 2012 11:563-75. (WB; Human) [PubMed:22704617]
5
Identification of autophagic vacuoles and regulators of autophagy in villous trophoblast from normal term pregnancies and in fetal growth restriction. Curtis S, Jones CJ, Garrod A, Hulme CH, Heazell AE. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2013 26:339-46. (IHC; Human) [PubMed:23039021]
6
Downregulation of Autophagy-Related Proteins 1, 5, and 16 in Testicular Germ Cell Tumors Parallels Lowered LC3B and Elevated p62 Levels, Suggesting Reduced Basal Autophagy. Liu H, He Z, Bode P, Moch H, Simon HU. Frontiers in oncology. 2018 September;8:366. [Full Text Article] [PubMed:30245976] [PMC:PMC6137693] Related Antibodies: LS-B2723.
7
Machine learning with autophagy-related proteins for discriminating renal cell carcinoma subtypes. Zhaoyue He, He Liu, Holger Moch, Hans-Uwe Simon. Scientific reports. 2020 Jan;10:720. [Full Text Article] [PubMed:31959887] [PMC:PMC6971298] Related Antibodies: LS-B2723.
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☰ Filters
Antibodies (101)
Proteins (10)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (101)
Recombinant (6)
Sandwich (1)
ATG16L1 / ATG16L (112)
Human (100)
Mouse (40)
Rat (25)
Bat (6)
Bovine (23)
Chicken (3)
Chimpanzee (15)
Dog (11)
Gibbon (15)
Guinea pig (9)
Hamster (4)
Horse (12)
Monkey (16)
Orangutan (18)
Pig (9)
Primate (5)
Rabbit (9)
Zebrafish (6)
IHC (37)
IHC-Fr (1)
IHC-P (27)
WB (92)
Flo (1)
ELISA (20)
ICC (2)
IF (8)
IP (3)
Peptide-ELISA (2)
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rabbit (86)
mouse (14)
goat (1)
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IHCPlus (8)
IgG (37)
IgG1 (7)
IgG1,k (6)
monoclonal mc (13)
polyclonal pc (88)
54CT27.2.6 (7)
5H9A11 (1)
8F8C2 (1)
OTI2A10 (2)
OTI5A2 (2)
96-Well Strip Plate (1)
APC (2)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (13)
Carrier-free (2)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
DY488 Conjugated (2)
DY550 Conjugated (2)
DY650 Conjugated (2)
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HRP Conjugated (11)
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Unconjugated (48)
aa1-100 (10)
aa1-284 (8)
aa342-607 (8)
aa1-277 (4)
aa1-607 (4)
aa121-170 (4)
aa215-264 (4)
aa254-303 (4)
aa38-87 (4)
aa441-490 (4)
aa81-130 (4)
60-140 aa, Internal (1)
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aa161-190 (1)
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aa35-260 (1)
aa454-483 (1)
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aa548-562 (1)
aa90-300 (1)
No (110)
Yes (2)
Tissue Homogenates (1)
GST (1)
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His (1)
His-GST-S (1)
His-SUMO (1)
His-T7 (1)
Myc-DDK (Flag) (4)
Human (8)
293T Cells (2)
E. coli (3)
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Wheat Germ Extract (2)
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Purified (1)
ATG16L1 / ATG16L Antibody - Anti-ATG16L1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ATG16L1 / ATG16L Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$431
ATG16L1 / ATG16L Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with Autophagy APG16L antibody (L176), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa161-190) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
ATG16L1 / ATG16L Antibody - Anti-ATG16L1 / ATG16L antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 3.75 ug/ml.
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ATG16L1 / ATG16L Goat anti-Human Polyclonal (aa548-562) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
ATG16L1 / ATG16L ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$792
ATG16L1 / ATG16L Antibody - Anti-ATG16L1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa1-100) Antibody
Mouse, Dog, Bovine, Rat, Primate, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
ATG16L1 / ATG16L Antibody - ATG16L1 Antibody - Western blot of ATG16L1 in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Mouse Polyclonal (aa1-100) Antibody
Mouse, Human
WB
Unconjugated
0.1 ml/$386
ATG16L1 / ATG16L Antibody - ATG16L1 Antibody - Western blot of ATG16L1 in HeLa whole cell extracts.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Mouse Polyclonal (aa1-100) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
0.1 ml/$416
ATG16L1 / ATG16L Antibody - ATG16L1 antibody Western blot of Fetal Liver lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa215-264) Antibody
Human
WB
Unconjugated
100 µl/$424
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
ATG16L1 / ATG16L Antibody - Anti-ATG16L1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa38-87) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATG16L1 / ATG16L Antibody - Anti-ATG16L1 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa254-303) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
ATG16L1 / ATG16L Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
IHC-P, SWB
Unconjugated
50 µg/$460
ATG16L1 / ATG16L Antibody - Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
IHC-P, SWB
Unconjugated
50 µg/$460
ATG16L1 / ATG16L Antibody - Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa90-300) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
ATG16L1 / ATG16L Antibody - Immunohistochemistry of paraffin-embedded human skin tissue using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (aa1-607) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ATG16L1 / ATG16L Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ATG16L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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ATG16L1 / ATG16L Mouse anti-Human Monoclonal (aa1-277) (OTI5A2) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
ATG16L1 / ATG16L Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-ATG16L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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ATG16L1 / ATG16L Mouse anti-Human Monoclonal (aa1-277) (Carrier-free) (OTI5A2) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rat, Human
IF, IHC, WB
Unconjugated
100 µl/$688
ATG16L1 / ATG16L Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using ATG16L1 Polyclonal Antibody at dilution of 1:45(×200)
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ATG16L1 / ATG16L Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer tissue  using ATG16L1 Polyclonal Antibody at dilution of 1:40(×200)
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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ATG16L1 / ATG16L Mouse anti-Human Monoclonal (54CT27.2.6) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
ATG16L1 / ATG16L Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ATG16L1 / ATG16L Antibody - Immunohistochemistry of paraffin-embedded human colon cancer tissue.
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ATG16L1 / ATG16L Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
20 µl/$275; 100 µl/$389
Viewing 1-25 of 112 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).