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ATG9A

autophagy related 9A

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and SUPT20H.

Gene Name: autophagy related 9A
Synonyms: ATG9A, APG9-like 1, Autophagy 9-like 1 protein, Autophagy-related protein 9A, MGD3208, MATG9, APG9 autophagy 9-like 1, APG9L1, Autophagy related 9A
Target Sequences: NM_024085 NP_076990.4 Q7Z3C6

Publications (3)

1
Silica nanoconstruct cellular toleration threshold in vitro. Herd HL, Malugin A, Ghandehari H. Journal of controlled release : official journal of the Controlled Release Society. 2011 153:40-8. (WB; Mouse, Human) [PubMed:21342660] [PMC:PMC3197243]
2
Identification of autophagic vacuoles and regulators of autophagy in villous trophoblast from normal term pregnancies and in fetal growth restriction. Curtis S, Jones CJ, Garrod A, Hulme CH, Heazell AE. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 2013 26:339-46. (IHC; Human) [PubMed:23039021]
3
Autophagy in Pancreatic Acinar Cells in Caerulein-treated Mice: Immunolocalization of Related Proteins and Their Potential as Markers of Pancreatitis. Zhang L, Zhang J, Shea K, Xu L, Tobin G, Knapton A, Sharron S, Rouse R. Toxicologic pathology. 2013 42:435-57. (ICC, WB; Human, Rat) [Full Text Article] [PubMed:23640381]

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).