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ATP1B4
ATPase, Na+/K+ transporting, beta 4 polypeptide
This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | ATPase, Na+/K+ transporting, beta 4 polypeptide |
| Family/Subfamily: | Transporter , ATPase - P type, beta subunit |
| Synonyms: | ATP1B4, Protein ATP1B4, Sodium/potassium-ATPase beta-m, X,K-ATPase beta-m subunit, X,K-ATPase subunit beta-m |
| Target Sequences: | NM_012069 NP_036201.1 Q9UN42 |
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