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Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
Gene Name: | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E |
Family/Subfamily: | Transporter , ATPase - F type |
Synonyms: | ATP5I, ATPase subunit e, HAS-e, ATP5K |
Target Sequences: | NM_007100 NP_009031.1 P56385 |
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