ATP6V0E1

ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1

ATP6V0E1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is possibly part of the V0 subunit. Since two nontranscribed pseudogenes have been found in dog, it is possible that the localization to chromosome 2 for this gene by radiation hybrid mapping is representing a pseudogene. Genomic mapping puts the chromosomal location on 5q35.3.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

ATP6V0E1 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human ATP6V0E1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67316

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.2 kDa

Price:

20 µg/$1,107

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ATP6V0E1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116989

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.2 kDa

Price:

100 µg/$494

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Human ATP6V0E1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79527

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

9.2 kDa

Price:

20 µg/$150

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Human ATP6V0E1 Protein (Recombinant GST) (Full Length) - LS-G31421

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

35.8 kDa

Price:

10 µg/$479; 25 µg/$670

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