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ATRIP

ATR interacting protein

ATRIP is an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: ATR interacting protein
Synonyms: ATRIP, AGS1, ATR-interacting protein, ATR interacting protein
Target Sequences: NM_130384 NP_569055.1 Q8WXE1

Publications (1)

1
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA. Choi JH, Lindsey-Boltz LA, Sancar A. Proceedings of the National Academy of Sciences of the United States of America. 2007 104:13301-6. [PubMed:17686975] [PMC:PMC1941640]

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Proteins (3)
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ATRIP (3)
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Myc-DDK (Flag) (3)
Human (2)
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HEK 293 Cells (2)
ATRIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
85.7 kDa
20 µg/$215
ATRIP Protein - Purified recombinant protein ATRIP was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
85.7 kDa
20 µg/$1,107
ATRIP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
85.7 kDa
100 µg/$710
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).