ATXN2 / SCA2 / Ataxin-2

ataxin 2

The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. Defects in this gene are the cause of spinocerebellar ataxia type 2 (SCA2). SCA2 belongs to the autosomal dominant cerebellar ataxias type I (ADCA I) which are characterized by cerebellar ataxia in combination with additional clinical features like optic atrophy, ophthalmoplegia, bulbar and extrapyramidal signs, peripheral neuropathy and dementia. SCA2 is caused by expansion of a CAG repeat in the coding region of this gene. This locus has been mapped to chromosome 12, and it has been determined that the diseased allele contains 37-50 CAG repeats, compared to 17-29 in the normal allele. Longer expansions result in earlier onset of the disease. Alternatively spliced transcript variants encoding different isoforms have been identified but their full length sequence has not been determined.

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Products

ELISA Kits (8)

Type

Sandwich (8)

Target

ATXN2 / SCA2 / Ataxin-2 (8)

Reactivity

Human (1)

Mouse (1)

Rat (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

12 x 8-Well Microstrips (1)

96-Well Strip Plate (7)

Publications

No (8)

Sample Type

Plasma (4)

Serum (4)

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Mouse ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F38254

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$771

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Human ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F37826

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Monkey ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41515

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Rat ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F38586

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Chicken ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41512

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41513

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41514

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit ATXN2 / SCA2 / Ataxin-2 (Sandwich ELISA) ELISA Kit - LS-F41516

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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