AUH

AU RNA binding protein/enoyl-CoA hydratase

The methylglutaconyl-CoA hydratase, mitochondrial protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity. A possible subcellular localization in the mitochondria has been demonstrated for the mouse homolog of this protein which shares 92% identity with the human protein. It has been suggested that AUH may have a novel role as a mitochondrial located AU-binding protein. Human AUH is expressed as a single mRNA species of 1.8 kb, and translated as a 40-kDa precursor protein which is subsequently processed to a 32-kDa mature form.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

AUH (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human AUH Protein (Recombinant GST, N-terminus) (aa44-135) - LS-G57867

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human AUH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84074

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.61 kDa

Price:

20 µg/$150

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Human AUH Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69200

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

29.1 kDa

Price:

20 µg/$1,107

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AUH Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118451

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.61 kDa

Price:

100 µg/$494

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Human AUH Protein (Recombinant His) - LS-G1058

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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