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Acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. Has a preference for arachidyl alcohol as well as decyl alcohol, demonstrating its relatively poor activity using saturated long chain alcohols (C16, C18, and C20).
Gene Name: | acyl-CoA wax alcohol acyltransferase 1 |
Synonyms: | AWAT1, DGAT2L3, DGA2 |
Target Sequences: | NP_001013597.1 Q58HT5 |
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