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C5AR2 / GPR77 / C5L2

complement component 5a receptor 2

C5AR2 / GPR77 / C5L2 is a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

Gene Name: complement component 5a receptor 2
Family/Subfamily: GPCR , Anaphylatoxin
Synonyms: C5AR2, G-protein coupled receptor 77, GPF77, GPR77, C5L2, G protein-coupled receptor 77
Target Sequences: NM_018485 NP_060955.1 Q9P296

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Products
Antibodies (25)
Primary (25)
C5AR2 / GPR77 / C5L2 (25)
Human (23)
Mouse (3)
Rat (1)
Monkey (1)
Primate (1)
IHC (8)
IHC-P (6)
WB (17)
Flo (2)
ELISA (12)
Peptide-ELISA (2)
rabbit (21)
mouse (3)
rat (1)
Product Group
GPCR Database Antibodies (4)
IHCPlus (3)
PathPlus Neuro (2)
IgG (16)
IgG2a,k (2)
IgG2b (1)
monoclonal mc (3)
polyclonal pc (22)
1A6 (1)
1D9-M12 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (20)
aa297-325 (7)
C-Terminus (2)
N-Terminus (2)
Extracellular Domain (1)
aa1-50 (1)
aa248-337 (1)
No (25)
C5AR2 / GPR77 / C5L2 Antibody - Brain, substantia nigra. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
C5AR2 / GPR77 / C5L2 Antibody - Brain, Amygdala
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Neuroscience
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
C5AR2 / GPR77 / C5L2 Antibody - Anti-C5L2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
C5AR2 / GPR77 / C5L2 Antibody - Western blot analysis of extracts of various cell lines, using C5AR2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
C5AR2 / GPR77 / C5L2 Antibody - Anti-Mouse C5aR2 (GPR77) (0.03µg/ml) staining of a mouse brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, WB
Unconjugated
100 µg/$491
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C5AR2 / GPR77 / C5L2 Mouse anti-Human Monoclonal (1D9-M12) Antibody
Human
Flo
Unconjugated
100 µg/$587
C5AR2 / GPR77 / C5L2 Antibody - Clone 1A6 human hippocampus paraffin section
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C5AR2 / GPR77 / C5L2 Mouse anti-Human Monoclonal (1A6) Antibody
Human
IHC-P
Unconjugated
200 µg/$672
C5AR2 / GPR77 / C5L2 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
C5AR2 / GPR77 / C5L2 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
C5AR2 / GPR77 / C5L2 Antibody - Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using C5AR2 Polyclonal Antibody at dilution of 1:25(×200)
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
C5AR2 / GPR77 / C5L2 Antibody - Anti-Human C5aR2 (GPR77) (0.03µg/ml) staining of A541 (A) and HeLa (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$491
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C5AR2 / GPR77 / C5L2 Rat anti-Mouse Monoclonal Antibody
Mouse
Flo
Unconjugated
100 µg/$896
C5AR2 / GPR77 / C5L2 Antibody - GPR77 Antibody western blot of A549 cell line lysates (35 ug/lane). The GPR77 antibody detected the GPR77 protein (arrow).
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa297-325) Antibody
Human
WB
Unconjugated
400 µl/$393
C5AR2 / GPR77 / C5L2 Antibody - Sample (30 ug of whole cell lysate). A: HeLa, B: Molt-4 . 10% SDS PAGE. C5L2 antibody diluted at 1:1000
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (aa248-337) Antibody
Human
WB
Unconjugated
100 µl/$450
C5AR2 / GPR77 / C5L2 Antibody - GPR77 Antibody western blot with human samples
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C5AR2 / GPR77 / C5L2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Primate
WB
Unconjugated
25 µg/$364; 100 µg/$511
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C5AR2 / GPR77 / C5L2 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-25 of 25 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).