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CALCRL / CGRP Receptor

calcitonin receptor-like

Calcitonin receptor-like receptor (CRLR) is an Adrenomedullin Receptor that requires two additional proteins to function: a chaperone protein RAMP (receptor activity modifying protein) and the component protein RCP. The function of CRLR depends on its interaction with RAMP. When coexpressed with RAMP1, CRLR acts as a receptor for calcitonin gene-related peptide (CGRP). In contrast, when CRLR is coexpressed with either RAMP2 or RAMP3, it acts as a receptor for adrenomedullin. Activation of the receptor leads to an increase in intracellular cyclic AMP. CRLR mediates the vasorelaxation of arteries, suggesting a potential role for the receptor in reaction to injury, particularly in the treatment of pulmonary hypertension.

Gene Name: calcitonin receptor-like
Family/Subfamily: GPCR , Adrenomedullin
Synonyms: CALCRL, CGRP type 1 receptor, Cgrp1 receptor, CRLR, Calcitonin receptor-like, CGRP receptor, CGRPR
Target Sequences: NM_005795 NP_005786.1 Q16602

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Products
Antibodies (22)
Primary (22)
CALCRL / CGRP Receptor (22)
Human (20)
Mouse (10)
Rat (11)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Goat (1)
Guinea pig (3)
Hamster (1)
Horse (4)
Monkey (4)
Orangutan (3)
Pig (1)
Rabbit (4)
Xenopus (1)
IHC (4)
IHC-P (2)
WB (17)
ELISA (8)
IP (1)
Peptide-ELISA (1)
rabbit (22)
Product Group
GPCR Database Antibodies (2)
PathPlus Neuro (2)
IgG (17)
polyclonal pc (20)
recombinant monoclonal rmc (2)
Biotin Conjugated (3)
CF Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (16)
aa108-157 (4)
aa436-461 (3)
C-Terminus (2)
aa340-367 (2)
Cytoplasmic Domain (1)
N-Terminus (1)
No (22)
CALCRL / CGRP Receptor Antibody - Anti-CALCRL  / CGRP Receptor antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CALCRL / CGRP Receptor Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
Fast Shipping
CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Xenopus, Rabbit, Goat, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
CALCRL / CGRP Receptor Antibody - CALCRL antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa108-157) Antibody
Human
WB
Unconjugated
100 µl/$424
CALCRL / CGRP Receptor Antibody - CALCRL antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa108-157) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
CALCRL / CGRP Receptor Antibody - CALCRL antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa108-157) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
CALCRL / CGRP Receptor Antibody - CALCRL antibody Western blot of Fetal Muscle lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa108-157) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Orangutan, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
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CALCRL / CGRP Receptor Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$832
CALCRL / CGRP Receptor Antibody - CALCRL Antibody western blot of CEM cell line lysates (35 ug/lane). The CALCRL antibody detected the CALCRL protein (arrow).
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa340-367) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
CALCRL / CGRP Receptor Antibody - Immunohistochemistry of paraffin-embedded Rat liver using CALCRL Polyclonal Antibody at dilution of 1:50.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CALCRL / CGRP Receptor Antibody - Western blot analysis of extracts of various cells.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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CALCRL / CGRP Receptor Rabbit Recombinant Monoclonal Antibody
IHC, WB
Unconjugated
10 µl/$299; 100 µl/$548
CALCRL / CGRP Receptor Antibody - Western blot analysis of CALCRL using 293 whole cells lysates
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa340-367) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CALCRL / CGRP Receptor Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µl/$801
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa436-461) Antibody
Human
ELISA
Unconjugated
200 µg/$1,027
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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CALCRL / CGRP Receptor Rabbit Recombinant Monoclonal Antibody
IP, WB
Unconjugated
10 µl/$299; 100 µl/$425
CALCRL / CGRP Receptor Antibody
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
CALCRL / CGRP Receptor Antibody - Western blot analysis of extracts of various cell lines, using CALCRL antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa436-461) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$1,109
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CALCRL / CGRP Receptor Rabbit anti-Human Polyclonal (aa436-461) (CF) Antibody
Human
ELISA
CF Conjugated
100 µl/$1,109
Viewing 1-22 of 22 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).