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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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Customer Service: (800) 227-6666 / (650) 697-3600


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CASP12 / Caspase 12

caspase 12

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

Gene Name: caspase 12
Family/Subfamily: Protease , Cysteine C14
Synonyms: CASP12, Caspase 12 pseudogene 1, Caspase 12, CASP-12, Caspase 12 (gene/pseudogene), Inactive caspase-12, CASP12P1
Target Sequences: AF486844 CAD13032.1 Q6UXS9

☰ Filters
Products
Antibodies (61)
Primary (61)
CASP12 / Caspase 12 (61)
Human (38)
Mouse (40)
Rat (23)
IHC (31)
IHC-P (7)
WB (53)
Flo (8)
ELISA (22)
ICC (7)
IF (11)
IP (3)
Peptide-ELISA (3)
rabbit (57)
goat (1)
rat (3)
Product Group
IHCPlus (1)
PathPlus Neuro (1)
IgG (34)
IgG1 (2)
IgG1,k (1)
monoclonal mc (3)
polyclonal pc (58)
12G6 (1)
14F4 (1)
14F7 (1)
APC (2)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (4)
Unconjugated (32)
aa1-244 (8)
aa1-413 (8)
aa165-193 (7)
aa1-92 (4)
Internal (2)
Pro99 (1)
aa100-116 (1)
aa100-321 (1)
aa183-205 (1)
aa2-17 (1)
aa232-244 (1)
aa50-99 (1)
aa71-84 (1)
No (61)
CASP12 / Caspase 12 Antibody - Anti-CASP12 / Caspase 12 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$440
CASP12 / Caspase 12 Antibody - Western blot of Caspase-12 in mouse skeletal muscle lysate in the 1) absence and 2) presence of immunizing peptide using Peptide-affinity Purified Polyclonal Antibody to Caspase-12 at 0.25 ug/ml. Goat anti-rabbit Ig HRP secondary antibody, and PicoTect ECL substrate solution, were used for this test.
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CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal (aa100-116) Antibody
Mouse
WB
Unconjugated
100 µg/$386
CASP12 / Caspase 12 Antibody - Anti-CASP12 / Caspase 12 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
CASP12 / Caspase 12 Antibody - Immunohistochemical staining of human liver tissue using caspase-12 antibody (small) at 10 ug/mL.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
CASP12 / Caspase 12 Antibody - CASP12 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa165-193) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
CASP12 / Caspase 12 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue using CASP12 Antibody at dilution of 1:100
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
CASP12 / Caspase 12 Antibody
Select
CASP12 / Caspase 12 Rat Monoclonal (14F7) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$392
CASP12 / Caspase 12 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using CASP12 Polyclonal Antibody at dilution of 1:50.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
CASP12 / Caspase 12 Antibody - CASP12 / Caspase 12 antibody. IHC(P): Human Breast Cancer Tissue.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa71-84) Antibody
Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
CASP12 / Caspase 12 Antibody - Western blot analysis using anti-caspase-12 (mouse), mAb (12G6) detecting, A) endogenous caspase-12 in mouse lung, liver, spleen and pancreas, and B) pro-caspase-12 in mouse MEF's.
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CASP12 / Caspase 12 Rat anti-Mouse Monoclonal (aa183-205) (12G6) Antibody
Mouse
ELISA, Flo, WB
Unconjugated
100 µg/$414
CASP12 / Caspase 12 Antibody - Western blot of Caspase12 antibody
Select
CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
Select
CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
CASP12 / Caspase 12 Antibody - Immunohistochemistry of paraffin-embedded human prostate using CASP12 antibody at dilution of 1:100 (20x lens).
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
CASP12 / Caspase 12 Antibody - Immunohistochemistry analysis of Caspase12 antibody in paraffin-embedded human heart tissue.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (aa50-99) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CASP12 / Caspase 12 Antibody - Immunohistochemical analysis of Caspase 12 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
CASP12 / Caspase 12 Antibody - Immunohistochemical staining of Caspase-12 in human heart tissue with Caspase-12 antibody at 10µg/ml.
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CASP12 / Caspase 12 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$522
CASP12 / Caspase 12 Antibody - 1:100 staining human kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CASP12 / Caspase 12 Rabbit anti-Human Polyclonal Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 61 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).