CASP12 / Caspase 12

caspase 12

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

CASP12 / Caspase 12 (4)

Publications

No (4)

Tag

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

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Rat CASP12 / Caspase 12 Protein (Recombinant His-T7) (aa1-244) - LS-G12617

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.4 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Mouse CASP12 / Caspase 12 Protein (Recombinant His-GST) (aa1-413) - LS-G12618

Source:

E. coli

Tag:

His-GST

Molecular Weight:

79.6 kDa

Price:

50 µg/$412; 10 µg/$276; 200 µg/$822; 100 µg/$657; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human CASP12 / Caspase 12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88843

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

20 µg/$150

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CASP12 / Caspase 12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130895

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.4 kDa

Price:

100 µg/$494

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