CASP4 / Caspase 4

caspase 4, apoptosis-related cysteine peptidase

Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-4 was initially identified as a homologous protein to Caspase-1 and the C. elegans Ced-3 which could induce apoptosis in transfected cells. More recent studies have shown that it can be activated by ER stress and has been suggested to be involved in multiple neuronal pathologies such as Alzheimer's disease. The rodent homolog is known as Caspase 4 and Caspase 11.

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Products

Proteins (14)

Type

Over-Expression Lysate (4)

Recombinant (10)

Target

CASP4 / Caspase 4 (14)

Publications

No (14)

Tag

6His, N-terminus (1)

GST (1)

His (5)

His, N-Terminal (2)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Bovine (2)

Human (8)

Mouse (2)

Source

293T Cells (2)

E. coli (9)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human CASP4 / Caspase 4 Protein (Recombinant 6His, N-terminus) (Gln81-Asn377) - LS-G26561

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

36.3 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484

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Human CASP4 / Caspase 4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87843

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.1 kDa

Price:

20 µg/$150

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Human CASP4 / Caspase 4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G87844

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

20 µg/$150

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CASP4 / Caspase 4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99373

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.1 kDa

Price:

100 µg/$494

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CASP4 / Caspase 4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108321

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

100 µg/$494

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Human CASP4 / Caspase 4 Protein (Recombinant His, N-Terminal) - LS-G144129

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

43.1 kDa

Price:

50 µg/$419

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Human CASP4 / Caspase 4 Protein (Recombinant His-T7) (aa944-1148) - LS-G23905

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.7 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human CASP4 / Caspase 4 Protein (Recombinant GST) (Full Length) - LS-G27747

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.21 kDa

Price:

10 µg/$479; 25 µg/$670

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Human CASP4 / Caspase 4 Protein (Recombinant His) (aa78-265) - LS-G14216

Source:

E. coli

Tag:

His

Molecular Weight:

22.4 kDa

Price:

10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796

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Human CASP4 / Caspase 4 Protein (Recombinant His) (aa290-377) - LS-G14218

Source:

E. coli

Tag:

His

Molecular Weight:

11.9 kDa

Price:

10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796

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Mouse CASP4 / Caspase 4 Protein (Recombinant His) (aa286-373) - LS-G14220

Source:

E. coli

Tag:

His

Molecular Weight:

11.8 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Bovine CASP4 / Caspase 4 Protein (Recombinant His) (aa81-270) - LS-G14219

Source:

E. coli

Tag:

His

Molecular Weight:

22.6 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Mouse CASP4 / Caspase 4 Protein (Recombinant His, N-Terminal) (aa81-266) - LS-G14222

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.5 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Bovine CASP4 / Caspase 4 Protein (Recombinant His) (aa290-377) - LS-G14221

Source:

E. coli

Tag:

His

Molecular Weight:

12.0 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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