CASP5 / Caspase 5

caspase 5, apoptosis-related cysteine peptidase

CASP5 / Caspase 5 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

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Products

Antibodies (42)

Proteins (9)

ELISA Kits (3)

Type

Development Kit (1)

Over-Expression Lysate (4)

Primary (42)

Recombinant (5)

Sandwich (2)

Target

CASP5 / Caspase 5 (54)

Reactivity

Human (45)

Mouse (12)

Rat (12)

Bovine (6)

Hamster (6)

Monkey (6)

Rabbit (6)

Application

IHC (2)

IHC-P (3)

WB (37)

ELISA (10)

ICC (1)

IF (2)

Peptide-ELISA (3)

Host

rabbit (41)

mouse (1)

Product Group

DevKit DuoPlus (1)

IHCPlus (2)

Isotype

IgG (25)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (41)

Clone

4F7 (1)

Format

96-Well Strip Plate (2)

Antibody Pair and Standard (1)

AP Conjugated (1)

APC (1)

APC Conjugated (2)

Biotin Conjugated (5)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Unconjugated (19)

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Epitope

aa145-327 (8)

aa251-300 (4)

290-370 aa, C-terminal (1)

80-160 aa, Internal (1)

Asp121 (1)

C-Terminus (1)

Internal (1)

aa102-151 (1)

aa312-361 (1)

aa341-386 (1)

p10, Cleaved-Ser331 (1)

p20, Cleaved-Asp121 (1)

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Publications

No (54)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

Plasma (1)

Serum (1)

Tissue Homogenates (3)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His, N-Terminal (2)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (7)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

Purification

Purified (1)

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IHC-plus™ CASP5 / Caspase 5 Antibody LS-B476

(4.0) Rating

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ CASP5 / Caspase 5 Antibody (aa102-151) LS-B13450

(4.0) Rating

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa102-151) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$515

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Human CASP5 / Caspase 5 (Sandwich ELISA) ELISA Kit - LS-F32781

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$587

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Human CASP5 / Caspase 5 (Sandwich ELISA) ELISA Kit - LS-F4360

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$764

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Human CASP5 / Caspase 5 Protein (Recombinant His, N-Terminal) - LS-G144031

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

47.7 kDa

Price:

50 µg/$419

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CASP5 / Caspase 5 Antibody LS-C806774

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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CASP5 / Caspase 5 Antibody LS-C464

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$460

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CASP5 / Caspase 5 Antibody (290-370 aa, C-terminal) LS-C380468

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (290-370 aa, C-terminal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CASP5 / Caspase 5 Antibody (80-160 aa, Internal) LS-C380469

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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CASP5 / Caspase 5 Antibody (p20, Cleaved-Asp121) LS-C825915

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (p20, Cleaved-Asp121) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CASP5 / Caspase 5 Antibody (p10, Cleaved-Ser331) LS-C825916

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (p10, Cleaved-Ser331) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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CASP5 / Caspase 5 Antibody (aa312-361) LS-C121053

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa312-361) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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CASP5 / Caspase 5 Antibody (clone 4F7) LS-C179792

Antibody:

CASP5 / Caspase 5 Mouse anti-Human Monoclonal (4F7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$403

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CASP5 / Caspase 5 Antibody LS-C677397

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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CASP5 / Caspase 5 Antibody (HRP) LS-C677400

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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CASP5 / Caspase 5 Antibody (Biotin) LS-C677398

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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CASP5 / Caspase 5 Antibody (FITC) LS-C677399

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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CASP5 / Caspase 5 Antibody (aa341-386) LS-C313697

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa341-386) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CASP5 / Caspase 5 Antibody (Asp121) LS-C341178

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Asp121) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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CASP5 / Caspase 5 Antibody (Internal) LS-C351914

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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CASP5 / Caspase 5 Antibody (C-Terminus) LS-C351913

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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CASP5 / Caspase 5 Antibody (aa251-300) LS-C135479

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa251-300) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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CASP5 / Caspase 5 Antibody LS-C833846

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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CASP5 / Caspase 5 Antibody (aa145-327) LS-C314614

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa145-327) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141

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CASP5 / Caspase 5 Antibody (aa145-327, HRP) LS-C708226

Antibody:

CASP5 / Caspase 5 Rabbit anti-Human Polyclonal (aa145-327) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439

• Unconjugated
• HRP

• Unconjugated
• HRP

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