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CCL11 / Eotaxin
chemokine (C-C motif) ligand 11
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections.
| Gene Name: | chemokine (C-C motif) ligand 11 |
| Family/Subfamily: | Intercrine , Intercrine beta |
| Synonyms: | CCL11, C-C motif chemokine 11, Eotaxin-1, SCYA11, Small-inducible cytokine A11, Eosinophil chemotactic protein, Eotaxin |
| Target Sequences: | NM_002986 NP_002977.1 P51671 |
Publications (2)
1
Eosinophils in Colorectal Neoplasms Associated with Expression of CCL11 and CCL24. Cho H, Lim SJ, Won KY, Bae GE, Kim GY, Min JW, Noh BJ. Journal of pathology and translational medicine. 2016 50:45-51. (IHC, WB; Human)
[Full Text Article]
[PubMed:26657310]
[PMC:PMC4734969]
2
Peripheral Nerve Single-Cell Analysis Identifies Mesenchymal Ligands that Promote Axonal Growth. Jeremy S Toma, Konstantina Karamboulas, Matthew J Carr, Adelaida Kolaj, Scott A Yuzwa, Neemat Mahmud, Mekayla A Storer, David R Kaplan, Freda D Miller. eNeuro. 2020 May;7: [Full Text Article]
[PubMed:32349983]
[PMC:PMC7294463]
☰ Filters
Products
Proteins
(26)
Type
Over-Expression Lysate
(2)
Recombinant
(24)
Target
CCL11 / Eotaxin
(26)
Publications
No
(26)
Tag
GST
(1)
GST, N-terminus
(1)
His
(2)
His-GST
(3)
His-GST, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Horse
(1)
Human
(13)
Mouse
(6)
Rat
(3)
Rhesus monkey
(1)
Source
293T Cells
(1)
E. coli
(23)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(13)
Low Endotoxin Level
Low endotoxin level
(13)
Biologically Active
Biologically active
(12)
Animal-free
Animal-free
(1)
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 8.4 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein migrates at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Glycine
10 µg/$294; 25 µg/$359; 100 µg/$731
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$517; 1 mg/$2,851
E. coli
None
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
8.3 kDa
20 µg/$370; 5 µg/$282
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 74 amino acid recombinant protein has a predicted molecular mass of approximately 8.4 kD. The DTT-reduced protein migrates at approximately 12 kD and non-reduced protein migrates at approximately 14 kD by SDS-PAGE. The N-terminal amino acid is Histidi
10 µg/$294; 25 µg/$359; 100 µg/$731
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.4 kDa
1 mg/$2,885; 20 µg/$376
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
8.4 kDa
1 mg/$2,880; 20 µg/$372
E. coli
His
12.3 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
E. coli
His-GST
38.9 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
None
Biologically active
8.4 kDa
5 µg/$282; 100 µg/$1,116; 500 µg/$2,095
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.4 kDa
5 µg/$268; 20 µg/$349
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
8.3 kDa
5 µg/$268; 20 µg/$349
E. coli
His-GST, N-terminus
38kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His-GST
40.8 kDa
10 µg/$279; 50 µg/$427; 100 µg/$682; 200 µg/$852; 1 mg/$1,950; 500 µg/$1,494; 5 mg/$2,983; 2 mg/$2,136
E. coli
His-GST
40.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
E. coli
His
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$342; 500 µg/$641; 20 µg/$254
Wheat Germ Extract
GST
33.88 kDa
10 µg/$479; 25 µg/$670
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~8 kDa
20 µg/$291; 100 µg/$494; 1 mg/$2,851
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.56kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
8.6 kDa
10 µg/$281; 50 µg/$414
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~9 kDa
20 µg/$291; 1 mg/$2,551
293T Cells
Myc-DDK (Flag)
10.73 kDa
20 µg/$150
Viewing 1-25
of 26
product results
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