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CCND3 / Cyclin D3

cyclin D3

Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

Gene Name: cyclin D3
Synonyms: CCND3, D3-type cyclin, G1/S-specific cyclin D3, G1/S-specific cyclin-D3, Cyclin D3
Target Sequences: NM_001760 NP_001751.1 P30281

☰ Filters
Products
Antibodies (80)
Primary (80)
CCND3 / Cyclin D3 (80)
Human (77)
Mouse (42)
Rat (36)
Bat (3)
Bovine (4)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (11)
Pig (3)
Sheep (3)
IHC (41)
IHC-Fr (1)
IHC-P (12)
WB (65)
Flo (8)
DB (14)
ELISA (22)
ICC (2)
IF (8)
IP (9)
Neut (5)
Peptide-ELISA (4)
rabbit (69)
mouse (11)
Product Group
PathPlus Cancer (1)
IgG (39)
IgG1 (9)
IgG2b (2)
monoclonal mc (11)
polyclonal pc (69)
TS106 (1)
APC (1)
APC Conjugated (6)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Azide-free (2)
Biotin Conjugated (7)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (7)
HRP Conjugated (6)
PE Conjugated (5)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (42)
pThr283 (12)
aa1-292 (10)
C-Terminus (7)
pSer264 (7)
220-300 aa (2)
Gly277 (2)
aa136-292 (1)
aa241-260 (1)
aa243-292 (1)
aa252-281 (1)
aa33-66 (1)
p283 (1)
No (80)
CCND3 / Cyclin D3 Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (aa252-281) Antibody
Mouse, Human
IHC-P, WB
Unconjugated
200 µl/$460
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (aa1-292) (TS106) Antibody
Human
IHC, WB
Unconjugated
100 µg/$884
Select
CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$412
CCND3 / Cyclin D3 Antibody - Immunohistochemistry with anti-Cyclin D3 antibody showing Cyclin D3 staining in nucleus of lymphocytes in human spleen at 20x and 40x (B & C). Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with rabbit anti-mouse Cyclin D3 antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH 4 universal AP polymer detection system and visualized with WARP RED.
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CCND3 / Cyclin D3 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, Flo, IHC, IP, WB
Unconjugated
100 µg/$567
CCND3 / Cyclin D3 Antibody - Immunohistochemistry with anti-Cyclin D3 antibody showing Cyclin D3 staining in nucleus of lymphocytes in human spleen at 20x and 40x (B & C). Formalin fixed/paraffin embedded sections were subjected to heat induced epitope retrieval (HIER) at pH 6.2 and then incubated with rabbit anti-mouse Cyclin D3 antibody at 4.0 µg/ml for 60 minutes. The reaction was developed using MACH 4 universal AP polymer detection system and visualized with WARP RED.
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CCND3 / Cyclin D3 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, Flo, IHC, IP, WB
Unconjugated
25 µl/$304
CCND3 / Cyclin D3 Antibody - 1:100 staining human kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (pThr283) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCND3 / Cyclin D3 Antibody - Immunohistochemistry of paraffin-embedded human tonsil tissue using antibody at 1:100 dilution.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (aa1-292) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (HRP) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IP, Neut, WB
HRP Conjugated
100 µl/$1,071
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (Biotin) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IP, Neut, WB
Biotin Conjugated
100 µl/$1,071
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (FITC) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IP, Neut, WB
FITC Conjugated
100 µl/$1,071
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (APC) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IP, Neut, WB
APC Conjugated
100 µl/$1,071
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (PE) Antibody
Mouse, Rat, Human, Monkey
Flo, IF, IHC, IP, Neut, WB
PE Conjugated
100 µl/$1,071
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
100 µg/$564
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal Antibody
Mouse, Human, Monkey
Flo, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$780
CCND3 / Cyclin D3 Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCND3 / Cyclin D3 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Cyclin D3 (Phospho-Thr283) Antibody. The picture on the right is blocked with the phospho peptide.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (pThr283) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCND3 / Cyclin D3 Antibody - Immunofluorescence staining of CCND3 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CCND3 polyclonal antibody (dilution ratio 1:1000) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to nucleus and cytoplasm.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$412
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (220-300 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (p283) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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CCND3 / Cyclin D3 Mouse anti-Human Monoclonal (aa241-260) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$665
CCND3 / Cyclin D3 Antibody - Western blot of Cyclin D3 antibody
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (220-300 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCND3 / Cyclin D3 Antibody - P-peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Cyclin D3 (Phospho-Thr283) Antibody.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (pThr283) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
CCND3 / Cyclin D3 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Cyclin D3 Antibody. The picture on the right is blocked with the synthesized peptide.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (aa243-292) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
CCND3 / Cyclin D3 Antibody - CCND3 / Cyclin D3 antibody AVARP03038_P050-NP_001751-CCND3 (cyclin D3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human muscle.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCND3 / Cyclin D3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
Viewing 1-25 of 80 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).