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CCR10 / GPR2

chemokine (C-C motif) receptor 10

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).

Gene Name: chemokine (C-C motif) receptor 10
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR10, C-C CKR-10, CC-CKR-10, CCR-10, C-C chemokine receptor type 10, CC chemokine receptor 10, G-protein coupled receptor 2, GPR2, G protein-coupled receptor 2
Target Sequences: NM_016602 NP_057686.2 P46092

Publications (1)

1
POL7085 or anti-CCL28 treatment inhibits development of post-paramyxoviral airway disease. Buelow BJ, Rohlfing M, Jung F, Douglas GJ, Grayson MH. Immunity, inflammation and disease. 2017 June;5:98-108. [Full Text Article] [PubMed:28474501] [PMC:PMC5418136] Related Antibodies: LS-C35337.

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Antibodies (29)
Primary (29)
CCR10 / GPR2 (29)
Human (27)
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rabbit (25)
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aa312-327 (1)
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Yes (1)
CCR10 / GPR2 Antibody - Anti-CCR10 / GPR2 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
CCR10 / GPR2 Antibody - Anti-CCR10 antibody IHC of human skin, capillaries. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
CCR10 / GPR2 Antibody - Anti-CCR10 antibody IHC of human capillaries. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Pig, Bat, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
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CCR10 / GPR2 Rat anti-Mouse Monoclonal (APC) (248918) Antibody
Mouse
Flo
APC Conjugated
100 Tests/$953
CCR10 / GPR2 Antibody - Anti-CCR10 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Dog, Pig, Bat, Human
IHC, IHC-P
Unconjugated
50 µg/$460
CCR10 / GPR2 Antibody - Anti-CCR10 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa350-362) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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CCR10 / GPR2 Goat anti-Mouse Polyclonal (aa4-31) Antibody
Mouse
ELISA, Flo, ICC, IHC, WB
Unconjugated
100 µg/$556
CCR10 / GPR2 Antibody - Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution of 1:100
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CCR10 / GPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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CCR10 / GPR2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$341
CCR10 / GPR2 Antibody - IHC of CCR10 antibody. Formalin-fixed, paraffin-embedded human tonsil.
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CCR10 / GPR2 Goat anti-Human Polyclonal (aa9-31) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
100 µg/$556
CCR10 / GPR2 Antibody - Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CCR10
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CCR10 / GPR2 Goat anti-Human Polyclonal (aa9-31) Antibody
Human
ELISA, Flo, IHC-P, WB
Unconjugated
0.1 mg/$500
CCR10 / GPR2 Antibody - IHC staining of FFPE human esophageal squamous cancer with CCR10 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal Antibody
Human
IHC-P, WB
Unconjugated
100 µg/$575
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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CCR10 / GPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
CCR10 / GPR2 Antibody - Western blot analysis of CCR10 using COLO205 whole cells lysates
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CCR10 / GPR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCR10 / GPR2 Antibody - WB of CCR10 / GPR2 antibody. All lanes: Anti-CCR10 at 0.5ug/ml. Lane 1: HELA Whole Cell Lysate at 40ug. Lane 2: SW620 Whole Cell Lysate at 40ug. Lane 3: A549 Whole Cell Lysate at 40ug. Lane 4: MM231 Whole Cell Lysate at 40ug. Lane 5: SMMC Whole Cell Lysate at 40ug. Predicted bind size: 38KD. Observed bind size: 38KD.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa312-327) Antibody
Rabbit, Mouse, Sheep, Bovine, Bat, Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
CCR10 / GPR2 Antibody - CCR10 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The CCR10 antibody detected the CCR10 protein (arrow).
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
WB
Unconjugated
400 µl/$393
CCR10 / GPR2 Antibody - CCR10 / GPR2 antibody Western Blot of Fetal Liver. Antibody dilution: 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CCR10 / GPR2 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Human
WB
Unconjugated
100 µl/$424
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).