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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

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CCR6

chemokine (C-C motif) receptor 6

CCR6 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.

Gene Name: chemokine (C-C motif) receptor 6
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR6, C-c chemokine receptor 6, CD196 antigen, BN-1, C-C chemokine receptor type 6, C-C CKR-6, Chemokine c-c motif receptor 6, CKRL3, CMKBR6, Chemokine (C-C) receptor 6, Chemokine receptor-like 3, Cc chemokine receptor 6, CC-CKR-6, CCR-6, DCR2, DRY6, G protein-coupled receptor 29, DRY-6, G-protein coupled receptor 29, GPR29, GPRCY4, Strl-22, STRL22, CD196, CKR-L3, GPR-CY4, LARC receptor
Target Sequences: NM_004367 NP_004358.2 P51684

Publications (2)

1
Expression of the chemokine receptor CCR6 correlates with a favorable prognosis in patients with adenocarcinoma of the lung. Minamiya Y, Saito H, Takahashi N, Ito M, Toda H, Ono T, Konno H, Motoyama S, Ogawa J. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 2011 32:197-202. [PubMed:20872189] Related Antibodies: LS-B2481.
2
Identification of the Single Immunodominant Region of the Native Human CC Chemokine Receptor 6 Recognized by Mouse Monoclonal Antibodies. Dorgham K, Dejou C, Piesse C, Gorochov G, Pène J, Yssel H. PloS one. 2016 11:e0157740. (Flo, Bind; Mouse) [Full Text Article] [PubMed:27336468] [PMC:PMC4919008] Related Antibodies: LS-A356.

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15.6 - 1000 pg/ml
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0.156 - 10 ng/ml
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96-Well Strip Plate
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Colorimetric - 450nm (TMB)
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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1 Plate/$579
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).