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CD34

CD34 molecule

CD34 is a monomeric cell surface antigen with a molecular mass of approximately 110 kD that is selectively expressed on human hematopoietic progenitor cells. CD34 is a member of a family of single-pass transmembrane sialomucin proteins that show expression on early hematopoietic and vascular-associated tissue. CD34 is also an important adhesion molecule and is required for T cells to enter lymph nodes. It is expressed on lymph node endothelia whereas the L-selectin to which it binds is on the T cell.

Gene Name: CD34 molecule
Synonyms: CD34, CD34 molecule, CD34 antigen, HPCA1
Target Sequences: NM_001773 NP_001764.1 P28906

Publications (13)

1
Characterization of MEC 14.7, a new monoclonal antibody recognizing mouse CD34: a useful reage for identifying and characterizing blood vessels and hematopoietic precursors. Garlanda C, Berthier R, Garin J, Stoppacciaro A, Ruco L, Vittet D, Gulino D, Matteucci C, Mantovani A, Vecchi A, Dejana E. European journal of cell biology. 1997 73:368-77. [PubMed:9270880]
2
A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants. Dong QG, Bernasconi S, Lostaglio S, De Calmanovici RW, Martin-Padura I, Breviario F, Garlanda C, Ramponi S, Mantovani A, Vecchi A. Arteriosclerosis, thrombosis, and vascular biology. 1997 17:1599-604. [PubMed:9301641]
3
Differential responsiveness to constitutive vs. inducible chemokines of immature and mature mouse dendritic cells. Vecchi A, Massimiliano L, Ramponi S, Luini W, Bernasconi S, Bonecchi R, Allavena P, Parmentier M, Mantovani A, Sozzani S. Journal of leukocyte biology. 1999 66:489-94. [PubMed:10496320]
4
Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. Trempus CS, Morris RJ, Bortner CD, Cotsarelis G, Faircloth RS, Reece JM, Tennant RW. The Journal of investigative dermatology. 2003 120:501-11. (ICC, IHC, Flo) [PubMed:12648211]
5
Organogenesis from dissociated cells: generation of mature cycling hair follicles from skin-derived cells. Zheng Y, Du X, Wang W, Boucher M, Parimoo S, Stenn K. The Journal of investigative dermatology. 2005 124:867-76. (IHC-P) [PubMed:15854024]
6
Generation and characterization of a mouse lymphatic endothelial cell line. Sironi M, Conti A, Bernasconi S, Fra AM, Pasqualini F, Nebuloni M, Lauri E, De Bortoli M, Mantovani A, Dejana E, Vecchi A. Cell and tissue research. 2006 325:91-100. [PubMed:16534603]
7
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK. The Journal of clinical investigation. 2008 118:3860-9. [PubMed:19033657] [PMC:PMC2579884]
8
The mobilization and effect of endogenous bone marrow progenitor cells in diabetic wound healing. Fiorina P, Pietramaggiori G, Scherer SS, Jurewicz M, Mathews JC, Vergani A, Thomas G, Orsenigo E, Staudacher C, La Rosa S, Capella C, Carothers A, Zerwes HG, Luzi L, Abdi R, Orgill DP. Cell transplantation. 2010 19:1369-81. [PubMed:20977829]
9
Endothelial cell HIF-1 and HIF-2 differentially regulate metastatic success. Branco-Price C, Zhang N, Schnelle M, Evans C, Katschinski DM, Liao D, Ellies L, Johnson RS. Cancer cell. 2012 21:52-65. [PubMed:22264788] [PMC:PMC3334270]
10
Effects of Sorafenib Dose on Acquired Reversible Resistance and Toxicity in Hepatocellular Carcinoma. Kuczynski EA, Lee CR, Man S, Chen E, Kerbel RS. Cancer research. 2015 June;75:2510-9. (Mouse) [Full Text Article] [PubMed:25908587]
11
Macrophages form functional vascular mimicry channels in vivo. Barnett FH, Rosenfeld M, Wood M, Kiosses WB, Usui Y, Marchetti V, Aguilar E, Friedlander M. Scientific reports. 2016 November;6:36659. (Mouse) [Full Text Article] [PubMed:27834402] [PMC:PMC5105153] Related Antibodies: LS-C62600.
12
Low-Level Laser Irradiation Promotes Proliferation and Differentiation on Apical Papilla Stem Cells. David Gutiérrez, Mahmoud Rouabhia, Javiera Ortiz, Diego Gaviria, Camilo Alfonso, Ana Muñoz, Carolina Inostroza. Journal of lasers in medical sciences. 2022 February;12:e75. [Full Text Article] [PubMed:35155160] [PMC:PMC8837851] Related Antibodies: LS-C204500.
13
Vascular endothelial growth inhibitor 174 is a negative regulator of aggressiveness and microvascular density in human clear cell renal cell carcinoma. Wu L, Li X, Ye L, Shayiremu D, Deng X, Zhang X, Jiang W, Yang Y, Gong K, Zhang N. Anticancer research. 2014 Feb;34:715-22. [Full Text Article] [PubMed:24511004] Related Antibodies: LS-B5262.
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CD34 Antibody - Anti-CD34 antibody IHC of human kidney, glomerulus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unmodified form of this product. Other forms have not been tested.
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Cancer Pathology
Cancer
CD34 Mouse anti-Human Monoclonal (Azide-free) (QBEnd-10) Antibody
Human, Non-Human Primates
Flo, Func, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Azide-free
0.1 mg/$460
CD34 Antibody - Anti-CD34 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse, Human
Flo, IHC, IHC-P, IP
Unconjugated
50 µg/$535
CD34 Antibody - Anti-CD34 antibody IHC of human kidney, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CD34 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$545
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CD34 Mouse anti-Human Monoclonal Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µg/$485
CD34 Antibody - Anti-CD34 antibody IHC of human kidney, glomeruli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:800.
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CD34 Mouse anti-Human Monoclonal (Concentrated) (QBEND-10) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Concentrated
50 µg/$575
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
250 µg/$406; 500 µg/$491
CD34 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD34 Rabbit anti-Human Polyclonal (aa366-382) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$460
CD34 Antibody - CD34 Antibody (MEC 14.7) - Hematopoietic Stem Cell Marker - IHC of CD34 on mouse renal cancer xenograft.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse, Rat
ELISA, Flo, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
CD34 Antibody - IHC of rat liver tissue using CD34 (Endothelial Cell Marker, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1) and
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CD34 Goat anti-Rat Polyclonal (aa37-293) Antibody
Rat
ELISA, IHC, IHC-Fr, WB
Unconjugated
100 µg/$962
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CD34 Goat anti-Pig Polyclonal (Extracellular Domain) Antibody
Pig
ELISA, WB
Unconjugated
100 µg/$940
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CD34 Rabbit anti-Human Polyclonal (aa366-382) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
CD34 Mouse anti-Human Monoclonal (4H11[APG]) Antibody
Human
Flo, ICC, IHC, IHC-P, WB
Unconjugated
0.1 mg/$460
CD34 Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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CD34 Rabbit anti-Human Monoclonal (EP88) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
50 µl/$460
CD34 Antibody - Anti-CD34 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CD34 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, IHC-Fr, IHC-P
FITC Conjugated
25 Tests/$460
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CD34 Mouse anti-Human Monoclonal (FITC) Antibody
Human
Flo, IHC, WB
FITC Conjugated
120 Tests/$763
CD34 Antibody - Surface staining of CD34+ cells in human peripheral blood with anti-CD34 (581) PerCP.
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CD34 Mouse anti-Human Monoclonal (PerCP) (581) Antibody
Human, Non-Human Primates
Flo, IHC-Fr
PerCP Conjugated
100 Tests/$411
CD34 Antibody - Immunocytochemical staining of chicken CD34 transfected COS-7 cells (A) with Mouse anti-Chicken CD34 detected using an AEC detection system. Mock transfected cells (B)(Image courtesy of the Roslin Institute)
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CD34 Mouse anti-Chicken Monoclonal (AV138) Antibody
Chicken
ELISA, ICC, WB
Unconjugated
0.1 mg/$406
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CD34 Mouse anti-Dog Monoclonal (1H6) Antibody
Dog
Flo, WB
Unconjugated
0.1 mg/$402
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CD34 Rat anti-Mouse Monoclonal (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
100 µg/$725
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CD34 Rat anti-Mouse Monoclonal (Concentrated) (MEC14.7) Antibody
Mouse
ELISA, Flo, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated, Concentrated
1 ml/$531
CD34 Antibody - Immunohistochemistry of paraffin-embedded human colon cancer at dilution of 1:100
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CD34 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
CD34 Antibody - Formalin-fixed, paraffin-embedded human tonsil stained with CD34 antibody (QBEnd/10 + HPCA1/763).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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CD34 Mouse anti-Human Monoclonal (N-Terminus) (Azide-free, BSA-free) (QBEnd/10 + HPCA1/763) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
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CD34 Mouse anti-Human Monoclonal (aa185-214) (PE) Antibody
Human
IHC, WB
PE Conjugated
200 µl/$952
CD34 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
CD34 Mouse anti-Human Monoclonal (aa185-214) (132CT29.1.5) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
CD34 Antibody - Anti-CD34 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 20 ug/ml.
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CD34 Mouse anti-Human Monoclonal (4H11) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Viewing 1-25 of 269 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).