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CDC7 is a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
Gene Name: | cell division cycle 7 |
Family/Subfamily: | Protein Kinase , CDC7 |
Synonyms: | CDC7, Cdc7 Kinase, CDC7-like 1, CDC7L1, HsCDC7, HuCDC7, CDC7-related kinase, Hsk1, MuCdc7 |
Target Sequences: | NM_003503 NP_003494.1 O00311 |
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